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Evolution of cyclizing 5-aminolevulinate synthases in the biosynthesis of actinomycete secondary metabolites: outcomes for genetic screening techniques

A combined approach, comprising PCR screening and genome mining, was used to unravel the diversity and phylogeny of genes encoding 5-aminolevulinic acid synthases (ALASs, hemA gene products) in streptomycetes-related strains. In actinomycetes, these genes were believed to be directly connected with...

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Detalles Bibliográficos
Autores principales:	Petříčková, Kateřina, Chroňáková, Alica, Zelenka, Tomáš, Chrudimský, Tomáš, Pospíšil, Stanislav, Petříček, Miroslav, Krištůfek, Václav
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525017/ https://www.ncbi.nlm.nih.gov/pubmed/26300877 http://dx.doi.org/10.3389/fmicb.2015.00814

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