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Validated prediction of pro-invasive growth factors using a transcriptome-wide invasion signature derived from a complex 3D invasion assay
The invasion of activated fibroblasts represents a key pathomechanism in fibrotic diseases, carcinogenesis and metastasis. Invading fibroblasts contribute to fibrotic extracellular matrix (ECM) formation and the initiation, progression, or resistance of cancer. To construct transcriptome-wide signat...
Autores principales: | Oehrle, Bettina, Burgstaller, Gerald, Irmler, Martin, Dehmel, Stefan, Grün, Jessica, Hwang, Tiffany, Krauss-Etschmann, Susanne, Beckers, Johannes, Meiners, Silke, Eickelberg, Oliver |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525140/ https://www.ncbi.nlm.nih.gov/pubmed/26243655 http://dx.doi.org/10.1038/srep12673 |
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