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Inhibition of dipeptidyl peptidase 8/9 impairs preadipocyte differentiation
Adipocytes are the primary cells in adipose tissue, and adipocyte dysfunction causes lipodystrophy, obesity and diabetes. The dipeptidyl peptidase (DPP) 4 family includes four enzymes, DPP4, DPP8, DPP9 and fibroblast activation protein (FAP). DPP4 family inhibitors have been used for the treatment o...
Autores principales: | Han, Ruijun, Wang, Xinying, Bachovchin, William, Zukowska, Zofia, Osborn, John W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525143/ https://www.ncbi.nlm.nih.gov/pubmed/26242871 http://dx.doi.org/10.1038/srep12348 |
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