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Conserved nematode signalling molecules elicit plant defenses and pathogen resistance

Plant-defense responses are triggered by perception of conserved microbe-associated molecular patterns (MAMPs), for example, flagellin or peptidoglycan. However, it remained unknown whether plants can detect conserved molecular patterns derived from plant-parasitic animals, including nematodes. Here...

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Detalles Bibliográficos
Autores principales: Manosalva, Patricia, Manohar, Murli, von Reuss, Stephan H., Chen, Shiyan, Koch, Aline, Kaplan, Fatma, Choe, Andrea, Micikas, Robert J., Wang, Xiaohong, Kogel, Karl-Heinz, Sternberg, Paul W., Williamson, Valerie M., Schroeder, Frank C., Klessig, Daniel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525156/
https://www.ncbi.nlm.nih.gov/pubmed/26203561
http://dx.doi.org/10.1038/ncomms8795
Descripción
Sumario:Plant-defense responses are triggered by perception of conserved microbe-associated molecular patterns (MAMPs), for example, flagellin or peptidoglycan. However, it remained unknown whether plants can detect conserved molecular patterns derived from plant-parasitic animals, including nematodes. Here we show that several genera of plant-parasitic nematodes produce small molecules called ascarosides, an evolutionarily conserved family of nematode pheromones. Picomolar to micromolar concentrations of ascr#18, the major ascaroside in plant-parasitic nematodes, induce hallmark defense responses including the expression of genes associated with MAMP-triggered immunity, activation of mitogen-activated protein kinases, as well as salicylic acid- and jasmonic acid-mediated defense signalling pathways. Ascr#18 perception increases resistance in Arabidopsis, tomato, potato and barley to viral, bacterial, oomycete, fungal and nematode infections. These results indicate that plants recognize ascarosides as a conserved molecular signature of nematodes. Using small-molecule signals such as ascarosides to activate plant immune responses has potential utility to improve economic and environmental sustainability of agriculture.