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Conserved nematode signalling molecules elicit plant defenses and pathogen resistance
Plant-defense responses are triggered by perception of conserved microbe-associated molecular patterns (MAMPs), for example, flagellin or peptidoglycan. However, it remained unknown whether plants can detect conserved molecular patterns derived from plant-parasitic animals, including nematodes. Here...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525156/ https://www.ncbi.nlm.nih.gov/pubmed/26203561 http://dx.doi.org/10.1038/ncomms8795 |
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author | Manosalva, Patricia Manohar, Murli von Reuss, Stephan H. Chen, Shiyan Koch, Aline Kaplan, Fatma Choe, Andrea Micikas, Robert J. Wang, Xiaohong Kogel, Karl-Heinz Sternberg, Paul W. Williamson, Valerie M. Schroeder, Frank C. Klessig, Daniel F. |
author_facet | Manosalva, Patricia Manohar, Murli von Reuss, Stephan H. Chen, Shiyan Koch, Aline Kaplan, Fatma Choe, Andrea Micikas, Robert J. Wang, Xiaohong Kogel, Karl-Heinz Sternberg, Paul W. Williamson, Valerie M. Schroeder, Frank C. Klessig, Daniel F. |
author_sort | Manosalva, Patricia |
collection | PubMed |
description | Plant-defense responses are triggered by perception of conserved microbe-associated molecular patterns (MAMPs), for example, flagellin or peptidoglycan. However, it remained unknown whether plants can detect conserved molecular patterns derived from plant-parasitic animals, including nematodes. Here we show that several genera of plant-parasitic nematodes produce small molecules called ascarosides, an evolutionarily conserved family of nematode pheromones. Picomolar to micromolar concentrations of ascr#18, the major ascaroside in plant-parasitic nematodes, induce hallmark defense responses including the expression of genes associated with MAMP-triggered immunity, activation of mitogen-activated protein kinases, as well as salicylic acid- and jasmonic acid-mediated defense signalling pathways. Ascr#18 perception increases resistance in Arabidopsis, tomato, potato and barley to viral, bacterial, oomycete, fungal and nematode infections. These results indicate that plants recognize ascarosides as a conserved molecular signature of nematodes. Using small-molecule signals such as ascarosides to activate plant immune responses has potential utility to improve economic and environmental sustainability of agriculture. |
format | Online Article Text |
id | pubmed-4525156 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Nature Pub. Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-45251562015-09-04 Conserved nematode signalling molecules elicit plant defenses and pathogen resistance Manosalva, Patricia Manohar, Murli von Reuss, Stephan H. Chen, Shiyan Koch, Aline Kaplan, Fatma Choe, Andrea Micikas, Robert J. Wang, Xiaohong Kogel, Karl-Heinz Sternberg, Paul W. Williamson, Valerie M. Schroeder, Frank C. Klessig, Daniel F. Nat Commun Article Plant-defense responses are triggered by perception of conserved microbe-associated molecular patterns (MAMPs), for example, flagellin or peptidoglycan. However, it remained unknown whether plants can detect conserved molecular patterns derived from plant-parasitic animals, including nematodes. Here we show that several genera of plant-parasitic nematodes produce small molecules called ascarosides, an evolutionarily conserved family of nematode pheromones. Picomolar to micromolar concentrations of ascr#18, the major ascaroside in plant-parasitic nematodes, induce hallmark defense responses including the expression of genes associated with MAMP-triggered immunity, activation of mitogen-activated protein kinases, as well as salicylic acid- and jasmonic acid-mediated defense signalling pathways. Ascr#18 perception increases resistance in Arabidopsis, tomato, potato and barley to viral, bacterial, oomycete, fungal and nematode infections. These results indicate that plants recognize ascarosides as a conserved molecular signature of nematodes. Using small-molecule signals such as ascarosides to activate plant immune responses has potential utility to improve economic and environmental sustainability of agriculture. Nature Pub. Group 2015-07-23 /pmc/articles/PMC4525156/ /pubmed/26203561 http://dx.doi.org/10.1038/ncomms8795 Text en Copyright © 2015, Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved. http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
spellingShingle | Article Manosalva, Patricia Manohar, Murli von Reuss, Stephan H. Chen, Shiyan Koch, Aline Kaplan, Fatma Choe, Andrea Micikas, Robert J. Wang, Xiaohong Kogel, Karl-Heinz Sternberg, Paul W. Williamson, Valerie M. Schroeder, Frank C. Klessig, Daniel F. Conserved nematode signalling molecules elicit plant defenses and pathogen resistance |
title | Conserved nematode signalling molecules elicit plant defenses and pathogen resistance |
title_full | Conserved nematode signalling molecules elicit plant defenses and pathogen resistance |
title_fullStr | Conserved nematode signalling molecules elicit plant defenses and pathogen resistance |
title_full_unstemmed | Conserved nematode signalling molecules elicit plant defenses and pathogen resistance |
title_short | Conserved nematode signalling molecules elicit plant defenses and pathogen resistance |
title_sort | conserved nematode signalling molecules elicit plant defenses and pathogen resistance |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525156/ https://www.ncbi.nlm.nih.gov/pubmed/26203561 http://dx.doi.org/10.1038/ncomms8795 |
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