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Snf1/AMP-activated protein kinase activates Arf3p to promote invasive yeast growth via a non-canonical GEF domain

Active GTP-bound Arf GTPases promote eukaryotic cell membrane trafficking and cytoskeletal remodelling. Arf activation is accelerated by guanine nucleotide-exchange factors (GEFs) using the critical catalytic glutamate in all known Sec7 domain sequences. Yeast Arf3p, a homologue of mammalian Arf6, i...

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Detalles Bibliográficos
Autores principales:	Hsu, Jia-Wei, Chen, Kuan-Jung, Lee, Fang-Jen S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Pub. Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525183/ https://www.ncbi.nlm.nih.gov/pubmed/26198097 http://dx.doi.org/10.1038/ncomms8840

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