MEG3 long noncoding RNA regulates the TGF-β pathway genes through formation of RNA–DNA triplex structures

Long noncoding RNAs (lncRNAs) regulate gene expression by association with chromatin, but how they target chromatin remains poorly understood. We have used chromatin RNA immunoprecipitation-coupled high-throughput sequencing to identify 276 lncRNAs enriched in repressive chromatin from breast cancer...

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Detalles Bibliográficos
Autores principales: Mondal, Tanmoy, Subhash, Santhilal, Vaid, Roshan, Enroth, Stefan, Uday, Sireesha, Reinius, Björn, Mitra, Sanhita, Mohammed, Arif, James, Alva Rani, Hoberg, Emily, Moustakas, Aristidis, Gyllensten, Ulf, Jones, Steven J.M., Gustafsson, Claes M, Sims, Andrew H, Westerlund, Fredrik, Gorab, Eduardo, Kanduri, Chandrasekhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525211/
https://www.ncbi.nlm.nih.gov/pubmed/26205790
http://dx.doi.org/10.1038/ncomms8743

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