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Mining Relation Reversals in the Evolution of SNOMED CT Using MapReduce

Relation reversals in ontological systems refer to such patterns as a path from concept A to concept B in one version becoming a path with the position of A and B switched in another version. We present a scalable approach, using cloud computing, to systematically extract all hierarchical relation r...

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Autores principales: Tao, Shiqiang, Cui, Licong, Zhu, Wei, Sun, Mengmeng, Bodenreider, Olivier, Zhang, Guo-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Informatics Association 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525241/
https://www.ncbi.nlm.nih.gov/pubmed/26306232
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author Tao, Shiqiang
Cui, Licong
Zhu, Wei
Sun, Mengmeng
Bodenreider, Olivier
Zhang, Guo-Qiang
author_facet Tao, Shiqiang
Cui, Licong
Zhu, Wei
Sun, Mengmeng
Bodenreider, Olivier
Zhang, Guo-Qiang
author_sort Tao, Shiqiang
collection PubMed
description Relation reversals in ontological systems refer to such patterns as a path from concept A to concept B in one version becoming a path with the position of A and B switched in another version. We present a scalable approach, using cloud computing, to systematically extract all hierarchical relation reversals among 8 SNOMED CT versions from 2009 to 2014. Taking advantage of our MapReduce algorithms for computing transitive closure and large-scale set operations, 48 reversals were found through 28 pairwise comparison of the 8 versions in 18 minutes using a 30-node local cloud, to completely cover all possible scenarios. Except for one, all such reversals occurred in three sub-hierarchies: Body Structure, Clinical Finding, and Procedure. Two (2) reversal pairs involved an uncoupling of the pair before the is-a coupling is reversed. Twelve (12) reversal pairs involved paths of length-two, and none (0) involved paths beyond length-two. Such reversals not only represent areas of potential need for additional modeling work, but also are important for identifying and handling cycles for comparative visualization of ontological evolution.
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spelling pubmed-45252412015-08-24 Mining Relation Reversals in the Evolution of SNOMED CT Using MapReduce Tao, Shiqiang Cui, Licong Zhu, Wei Sun, Mengmeng Bodenreider, Olivier Zhang, Guo-Qiang AMIA Jt Summits Transl Sci Proc Articles Relation reversals in ontological systems refer to such patterns as a path from concept A to concept B in one version becoming a path with the position of A and B switched in another version. We present a scalable approach, using cloud computing, to systematically extract all hierarchical relation reversals among 8 SNOMED CT versions from 2009 to 2014. Taking advantage of our MapReduce algorithms for computing transitive closure and large-scale set operations, 48 reversals were found through 28 pairwise comparison of the 8 versions in 18 minutes using a 30-node local cloud, to completely cover all possible scenarios. Except for one, all such reversals occurred in three sub-hierarchies: Body Structure, Clinical Finding, and Procedure. Two (2) reversal pairs involved an uncoupling of the pair before the is-a coupling is reversed. Twelve (12) reversal pairs involved paths of length-two, and none (0) involved paths beyond length-two. Such reversals not only represent areas of potential need for additional modeling work, but also are important for identifying and handling cycles for comparative visualization of ontological evolution. American Medical Informatics Association 2015-03-23 /pmc/articles/PMC4525241/ /pubmed/26306232 Text en ©2015 AMIA - All rights reserved. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose
spellingShingle Articles
Tao, Shiqiang
Cui, Licong
Zhu, Wei
Sun, Mengmeng
Bodenreider, Olivier
Zhang, Guo-Qiang
Mining Relation Reversals in the Evolution of SNOMED CT Using MapReduce
title Mining Relation Reversals in the Evolution of SNOMED CT Using MapReduce
title_full Mining Relation Reversals in the Evolution of SNOMED CT Using MapReduce
title_fullStr Mining Relation Reversals in the Evolution of SNOMED CT Using MapReduce
title_full_unstemmed Mining Relation Reversals in the Evolution of SNOMED CT Using MapReduce
title_short Mining Relation Reversals in the Evolution of SNOMED CT Using MapReduce
title_sort mining relation reversals in the evolution of snomed ct using mapreduce
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525241/
https://www.ncbi.nlm.nih.gov/pubmed/26306232
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