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Auxiliary KCNE subunits modulate both homotetrameric Kv2.1 and heterotetrameric Kv2.1/Kv6.4 channels

The diversity of the voltage-gated K(+) (Kv) channel subfamily Kv2 is increased by interactions with auxiliary β-subunits and by assembly with members of the modulatory so-called silent Kv subfamilies (Kv5-Kv6 and Kv8-Kv9). However, it has not yet been investigated whether these two types of modulat...

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Detalles Bibliográficos
Autores principales: David, Jens-Peter, Stas, Jeroen I., Schmitt, Nicole, Bocksteins, Elke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525287/
https://www.ncbi.nlm.nih.gov/pubmed/26242757
http://dx.doi.org/10.1038/srep12813