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A New Era of Laparoscopic Revision of Kasai Portoenterostomy for the Treatment of Biliary Atresia

Purpose. Kasai portoenterostomy is the standard therapy for biliary atresia (BA). If Kasai is unsuccessful, there is controversy over whether revision of Kasai restores adequate biliary drainage. Although there are several reports of laparoscopic Kasai (Lap-Kasai), none has described laparoscopic re...

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Autores principales: Murase, Naruhiko, Uchida, Hiroo, Ono, Yasuyuki, Tainaka, Takahisa, Yokota, Kazuki, Tanano, Akihide, Shirota, Chiyoe, Shirotsuki, Ryo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525460/
https://www.ncbi.nlm.nih.gov/pubmed/26266251
http://dx.doi.org/10.1155/2015/173014
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author Murase, Naruhiko
Uchida, Hiroo
Ono, Yasuyuki
Tainaka, Takahisa
Yokota, Kazuki
Tanano, Akihide
Shirota, Chiyoe
Shirotsuki, Ryo
author_facet Murase, Naruhiko
Uchida, Hiroo
Ono, Yasuyuki
Tainaka, Takahisa
Yokota, Kazuki
Tanano, Akihide
Shirota, Chiyoe
Shirotsuki, Ryo
author_sort Murase, Naruhiko
collection PubMed
description Purpose. Kasai portoenterostomy is the standard therapy for biliary atresia (BA). If Kasai is unsuccessful, there is controversy over whether revision of Kasai restores adequate biliary drainage. Although there are several reports of laparoscopic Kasai (Lap-Kasai), none has described laparoscopic revision (Lap-revision). The purposes of this study were to evaluate the feasibility and efficacy of Lap-revision. Methods. 65 patients underwent open Kasai between November 2001 and November 2013, and 12 patients underwent Lap-Kasai between December 2013 to January 2015. The indications for revision included bile flow cessation and recurrent cholangitis. Clinical data were compared between open and laparoscopic revisions of Kasai. Results. Open revision of Kasai was performed in 20 patients after open Kasai, and Lap-revision was performed in 4 patients after Lap-Kasai. Lap-revision was completed without conversion or major complication in any patient. The bilirubin level was normalized by Lap-revision in all four patients, and three of them were alive with their native liver. Open and laparoscopic revisions of Kasai were comparable in terms of the operation time, blood loss, and surgical outcomes. Conclusion. Lap-revision is a feasible and effective method for the treatment of BA and might herald a new era for the treatment of this disease.
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spelling pubmed-45254602015-08-11 A New Era of Laparoscopic Revision of Kasai Portoenterostomy for the Treatment of Biliary Atresia Murase, Naruhiko Uchida, Hiroo Ono, Yasuyuki Tainaka, Takahisa Yokota, Kazuki Tanano, Akihide Shirota, Chiyoe Shirotsuki, Ryo Biomed Res Int Clinical Study Purpose. Kasai portoenterostomy is the standard therapy for biliary atresia (BA). If Kasai is unsuccessful, there is controversy over whether revision of Kasai restores adequate biliary drainage. Although there are several reports of laparoscopic Kasai (Lap-Kasai), none has described laparoscopic revision (Lap-revision). The purposes of this study were to evaluate the feasibility and efficacy of Lap-revision. Methods. 65 patients underwent open Kasai between November 2001 and November 2013, and 12 patients underwent Lap-Kasai between December 2013 to January 2015. The indications for revision included bile flow cessation and recurrent cholangitis. Clinical data were compared between open and laparoscopic revisions of Kasai. Results. Open revision of Kasai was performed in 20 patients after open Kasai, and Lap-revision was performed in 4 patients after Lap-Kasai. Lap-revision was completed without conversion or major complication in any patient. The bilirubin level was normalized by Lap-revision in all four patients, and three of them were alive with their native liver. Open and laparoscopic revisions of Kasai were comparable in terms of the operation time, blood loss, and surgical outcomes. Conclusion. Lap-revision is a feasible and effective method for the treatment of BA and might herald a new era for the treatment of this disease. Hindawi Publishing Corporation 2015 2015-07-22 /pmc/articles/PMC4525460/ /pubmed/26266251 http://dx.doi.org/10.1155/2015/173014 Text en Copyright © 2015 Naruhiko Murase et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Murase, Naruhiko
Uchida, Hiroo
Ono, Yasuyuki
Tainaka, Takahisa
Yokota, Kazuki
Tanano, Akihide
Shirota, Chiyoe
Shirotsuki, Ryo
A New Era of Laparoscopic Revision of Kasai Portoenterostomy for the Treatment of Biliary Atresia
title A New Era of Laparoscopic Revision of Kasai Portoenterostomy for the Treatment of Biliary Atresia
title_full A New Era of Laparoscopic Revision of Kasai Portoenterostomy for the Treatment of Biliary Atresia
title_fullStr A New Era of Laparoscopic Revision of Kasai Portoenterostomy for the Treatment of Biliary Atresia
title_full_unstemmed A New Era of Laparoscopic Revision of Kasai Portoenterostomy for the Treatment of Biliary Atresia
title_short A New Era of Laparoscopic Revision of Kasai Portoenterostomy for the Treatment of Biliary Atresia
title_sort new era of laparoscopic revision of kasai portoenterostomy for the treatment of biliary atresia
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525460/
https://www.ncbi.nlm.nih.gov/pubmed/26266251
http://dx.doi.org/10.1155/2015/173014
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