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Dimethylfumarate protects against TNF-α-induced secretion of inflammatory cytokines in human endothelial cells

BACKGROUND: Inflammation, angiogenesis and oxidative stress have been implicated in the pathogenesis of various vascular diseases. Recent evidence suggests that dimethylfumarate (DMF), an antiposriatic and anti-multiple sclerosis agent, possesses anti-inflammatory, anti-oxidative and anti-angiogenic...

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Detalles Bibliográficos
Autores principales: Gerhardt, Simon, König, Veronika, Doll, Monika, Hailemariam-Jahn, Tsige, Hrgovic, Igor, Zöller, Nadja, Kaufmann, Roland, Kippenberger, Stefan, Meissner, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525722/
https://www.ncbi.nlm.nih.gov/pubmed/26246800
http://dx.doi.org/10.1186/s12950-015-0094-z