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Hepatoprotective effect of juglone on dimethylnitrosamine-induced liver fibrosis and its effect on hepatic antioxidant defence and the expression levels of α-SMA and collagen III

The present study aimed to investigate the antifibrotic effects of juglone on dimethylnitrosamine (DMN)-induced fibrosis in rats. Juglone, which is a quinone, significantly decreased DMN-induced rat hepatic fibrosis, which was associated with increased superoxide dismutase (SOD) activity, decreased...

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Detalles Bibliográficos
Autores principales: ZHOU, DE-JIANG, MU, DONG, JIANG, MING-DE, ZHENG, SHU-MEI, ZHANG, YONG, HE, SHENG, WENG, MIN, ZENG, WEI-ZHENG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526056/
https://www.ncbi.nlm.nih.gov/pubmed/26126609
http://dx.doi.org/10.3892/mmr.2015.3992