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Hepatoprotective effect of juglone on dimethylnitrosamine-induced liver fibrosis and its effect on hepatic antioxidant defence and the expression levels of α-SMA and collagen III
The present study aimed to investigate the antifibrotic effects of juglone on dimethylnitrosamine (DMN)-induced fibrosis in rats. Juglone, which is a quinone, significantly decreased DMN-induced rat hepatic fibrosis, which was associated with increased superoxide dismutase (SOD) activity, decreased...
Autores principales: | ZHOU, DE-JIANG, MU, DONG, JIANG, MING-DE, ZHENG, SHU-MEI, ZHANG, YONG, HE, SHENG, WENG, MIN, ZENG, WEI-ZHENG |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526056/ https://www.ncbi.nlm.nih.gov/pubmed/26126609 http://dx.doi.org/10.3892/mmr.2015.3992 |
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