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Vorinostat protects against calcium oxalate-induced kidney injury in mice

The present study aimed to examine the effect of the histone deacetylase inhibitor, vorinostat (SAHA), on renal function in a calcium oxalate crystal mouse model, and to investigate the mechanism underlying the renoprotective effect of SAHA. Calcium oxalate crystal formation was induced in 8 week-ol...

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Detalles Bibliográficos
Autores principales: WANG, LI, CHEN, WEI, PENG, ZHONGJIANG, LIU, CHANGCHENG, ZHANG, CAIHONG, GUO, ZHIYONG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526060/
https://www.ncbi.nlm.nih.gov/pubmed/26095064
http://dx.doi.org/10.3892/mmr.2015.3964