Cargando…

Activation of autophagy in rat brain cells following focal cerebral ischemia reperfusion through enhanced expression of Atg1/pULK and LC3

The present study aimed to investigate the activation of Atg1/pULK, and LC3 in the cerebral cortex following focal cerebral ischemia reperfusion (CIR) injury, thereby examining its effect on autophagy in brain cells. Rat CIR models were established using the technique of middle cerebral artery occlu...

Descripción completa

Detalles Bibliográficos
Autores principales:	YU, JINGWEI, BAO, CUIFEN, DONG, YANRU, LIU, XIA
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526088/ https://www.ncbi.nlm.nih.gov/pubmed/26018745 http://dx.doi.org/10.3892/mmr.2015.3850

Ejemplares similares

Receptor-interacting protein kinase 3-mediated programmed cell necrosis in rats subjected to focal cerebral ischemia-reperfusion injury
por: DONG, YANRU, et al.
Publicado: (2016)

Rapamycin induces autophagy to alleviate acute kidney injury following cerebral ischemia and reperfusion via the mTORC1/ATG13/ULK1 signaling pathway
por: Su, Yang, et al.
Publicado: (2018)

Recruitment and Activation of the ULK1/Atg1 Kinase Complex in Selective Autophagy
por: Turco, Eleonora, et al.
Publicado: (2020)

Neuroprotective effects of curdione against focal cerebral ischemia reperfusion injury in rats
por: Li, Xing-Jie, et al.
Publicado: (2017)

Improvement of the suture-occluded method in rat models of focal cerebral ischemia-reperfusion
por: ZHANG, PING, et al.
Publicado: (2014)

Reperfusion Promotes Mitochondrial Dysfunction following Focal Cerebral Ischemia in Rats
por: Li, Jun, et al.
Publicado: (2012)

Reperfusion Promotes Mitochondrial Biogenesis following Focal Cerebral Ischemia in Rats
por: Xie, Yuying, et al.
Publicado: (2014)

Hydrogen sulfide intervention in focal cerebral ischemia/reperfusion injury in rats
por: Li, Xin-juan, et al.
Publicado: (2015)

The protective role of verbenalin in rat model of focal cerebral ischemia reperfusion
por: Cao, Lihua, et al.
Publicado: (2018)

Synthesis and Protective Effect of Scutellarein on Focal Cerebral Ischemia/Reperfusion in Rats
por: Qian, Lihua, et al.
Publicado: (2012)

The deubiquitinase Leon/USP5 interacts with Atg1/ULK1 and antagonizes autophagy
por: Pai, Yueh-Ling, et al.
Publicado: (2023)

Protective effect of chlorogenic acid on the focal cerebral ischemia reperfusion rat models
por: Miao, Mingsan, et al.
Publicado: (2017)

Effect of Tetramethylpyrazine on Neuroplasticity after Transient Focal Cerebral Ischemia Reperfusion in Rats
por: Lin, Junbin, et al.
Publicado: (2021)

ULK1-mediated phosphorylation of ATG14 promotes autophagy and is impaired in Huntington’s disease models
por: Wold, Mitchell S., et al.
Publicado: (2016)

Autophagy initiation by ULK complex assembly on ER tubulovesicular regions marked by ATG9 vesicles
por: Karanasios, Eleftherios, et al.
Publicado: (2016)

Endothelial Atg7 Deficiency Ameliorates Acute Cerebral Injury Induced by Ischemia/Reperfusion
por: Wang, Hui-Jie, et al.
Publicado: (2018)

The effects of gabapentin pretreatment on brain injury induced by focal cerebral ischemia/reperfusion in the rat
por: Kim, Yoo-kyung, et al.
Publicado: (2010)

Expression profiles of microRNAs after focal cerebral ischemia/reperfusion injury in rats☆
por: Zhai, Fengguo, et al.
Publicado: (2012)

Hemopexin alleviates cognitive dysfunction after focal cerebral ischemia-reperfusion injury in rats
por: Dong, Beibei, et al.
Publicado: (2019)

Effects of the Rabdosia rubescens total flavonoids on focal cerebral ischemia reperfusion model in rats
por: Miao, Mingsan, et al.
Publicado: (2017)

ULK1-ATG13 and their mitotic phospho-regulation by CDK1 connect autophagy to cell cycle
por: Li, Zhiyuan, et al.
Publicado: (2020)

Puerarin protects rat brain against ischemia/reperfusion injury by suppressing autophagy via the AMPK-mTOR-ULK1 signaling pathway
por: Wang, Jin-Feng, et al.
Publicado: (2018)

Neuroprotective Effect of Phosphocreatine on Focal Cerebral Ischemia-Reperfusion Injury
por: Li, Tiegang, et al.
Publicado: (2012)

Structure of the human ATG12~ATG5 conjugate required for LC3 lipidation in autophagy
por: Otomo, Chinatsu, et al.
Publicado: (2012)

Effects of irisin on the dysfunction of blood–brain barrier in rats after focal cerebral ischemia/reperfusion
por: Guo, Peipei, et al.
Publicado: (2019)

Regulation of mATG9 trafficking by Src- and ULK1-mediated phosphorylation in basal and starvation-induced autophagy
por: Zhou, Changqian, et al.
Publicado: (2017)

A reversible phospho-switch mediated by ULK1 regulates the activity of autophagy protease ATG4B
por: Pengo, N., et al.
Publicado: (2017)

Activation of autophagy depends on Atg1/Ulk1-mediated phosphorylation and inhibition of the Hsp90 chaperone machinery
por: Backe, Sarah J., et al.
Publicado: (2023)

Music Therapy Alleviates Motor Dysfunction in Rats With Focal Cerebral Ischemia–Reperfusion Injury by Regulating BDNF Expression
por: Chen, Weiguan, et al.
Publicado: (2021)

Neuroprotective effect of penehyclidine hydrochloride on focal cerebral ischemia-reperfusion injury★
por: Yu, Cuicui, et al.
Publicado: (2013)

Melatonin combined with exercise cannot alleviate cerebral injury in a rat model of focal cerebral ischemia/reperfusion injury
por: Lee, Seunghoon, et al.
Publicado: (2012)

Focal cerebral ischemia in the TNFalpha-transgenic rat
por: Pettigrew, L Creed, et al.
Publicado: (2008)

Interaction Between FIP200 and ATG16L1 Distinguishes ULK1 Complex-Dependent and -Independent Autophagy
por: Gammoh, Noor, et al.
Publicado: (2012)

LicA induces autophagy through ULK1/Atg13 and ROS pathway in human hepatocellular carcinoma cells
por: Niu, Qiang, et al.
Publicado: (2018)

Sodium hydrosulfide attenuates cerebral ischemia/reperfusion injury by suppressing overactivated autophagy in rats
por: Jiang, Wen‐Wu, et al.
Publicado: (2017)

SIK2 Improving Mitochondrial Autophagy Restriction Induced by Cerebral Ischemia-Reperfusion in Rats
por: Zhang, Ran, et al.
Publicado: (2022)

Ischemic postconditioning may not influence early brain injury induced by focal cerebral ischemia/reperfusion in rats
por: Kim, Yoo Kyung, et al.
Publicado: (2010)

Effect of Sargentodoxa cuneata total phenolic acids on focal cerebral ischemia reperfusion injury rats model
por: Bai, Ming, et al.
Publicado: (2019)

Progesterone induces neuroprotection following reperfusion-promoted mitochondrial dysfunction after focal cerebral ischemia in rats
por: Andrabi, Syed Suhail, et al.
Publicado: (2017)

Effect of Panax notoginseng Saponins on Focal Cerebral Ischemia-Reperfusion in Rat Models: A Meta-Analysis
por: Sun, Tao, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_bh5mgbun30cj3g0d3pdv2k3old