Cargando…

Brachyury: A sensitive marker, but not a prognostic factor, for skull base chordomas

Patients with skull base chordomas have a poor prognosis, and the role of the protein expression of brachyury in chordomas remains to be fully elucidated. The present study used immunohistochemistry to analyze 57 cases of skull base chordoma, and analyzed the clinical data of the patients. The resul...

Descripción completa

Detalles Bibliográficos
Autores principales:	WANG, KE, TIAN, KAIBING, WANG, LIANG, WU, ZHEN, REN, CONG, HAO, SHUYU, FENG, JIE, LI, JUNHUA, WAN, HONG, JIA, GUIJUN, ZHANG, LIWEI, ZHANG, JUNTING
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526090/ https://www.ncbi.nlm.nih.gov/pubmed/26099340 http://dx.doi.org/10.3892/mmr.2015.3976

Ejemplares similares

The Brachyury Gly177Asp SNP Is not Associated with a Risk of Skull Base Chordoma in the Chinese Population
por: Wu, Zhen, et al.
Publicado: (2013)

Factors for tumor progression in patients with skull base chordoma
por: Wang, Liang, et al.
Publicado: (2016)

PTEN is recognized as a prognostic-related biomarker and inhibits proliferation and invasiveness of skull base chordoma cells
por: Tian, Kaibing, et al.
Publicado: (2022)

Tissue Microarray Immunohistochemical Detection of Brachyury Is Not a Prognostic Indicator in Chordoma
por: Zhang, Linlin, et al.
Publicado: (2013)

Inhibition Of Glycogen Synthase Kinase 3 Beta Suppresses The Growth And Survival Of Skull Base Chordoma Cells By Downregulating Brachyury Expression
por: Yan, Xudong, et al.
Publicado: (2019)

Identification of the Different Roles and Potential Mechanisms of T Isoforms in the Tumor Recurrence and Cell Cycle of Chordomas
por: Ma, Junpeng, et al.
Publicado: (2019)

Small-molecule targeting of brachyury transcription factor addiction in chordoma
por: Sharifnia, Tanaz, et al.
Publicado: (2019)

From Notochord Formation to Hereditary Chordoma: The Many Roles of Brachyury
por: Nibu, Yutaka, et al.
Publicado: (2013)

Brachyury: A Diagnostic Marker for the Differential Diagnosis of Chordoma and Hemangioblastoma versus Neoplastic Histological Mimickers
por: Barresi, Valeria, et al.
Publicado: (2014)

Active receptor tyrosine kinases, but not Brachyury, are sufficient to trigger chordoma in zebrafish
por: D'Agati, Gianluca, et al.
Publicado: (2019)

Experimental Study on Differences in Clivus Chordoma Bone Invasion: An iTRAQ-Based Quantitative Proteomic Analysis
por: Wu, Zhen, et al.
Publicado: (2015)

Hemorrhagic Skull Base Chordoma Presenting As Chordoma Apoplexy
por: Uysal, Ece, et al.
Publicado: (2021)

Methylation-based reclassification and risk stratification of skull-base chordomas
por: Huo, Xulei, et al.
Publicado: (2022)

Clinical response to nivolumab in an INI1-deficient pediatric chordoma correlates with immunogenic recognition of brachyury
por: Williamson, Laura M., et al.
Publicado: (2021)

Multivariate Analysis and Validation of the Prognostic Factors for Skull Base Chordoma
por: Teng, Chubei, et al.
Publicado: (2021)

Identification of tumor associated immune responses against brachyury, a transcription factor and driver of EMT, in chordoma patients receiving a yeast-brachyury vaccine (gi-6301)
por: Donahue, Renee N, et al.
Publicado: (2014)

Targeted brachyury degradation disrupts a highly specific autoregulatory program controlling chordoma cell identity
por: Sheppard, Hadley E., et al.
Publicado: (2021)

Prognostic Value of Cumulative Score Based on Preoperative Fibrinogen and Albumin Level in Skull Base Chordoma
por: Li, Mingxuan, et al.
Publicado: (2020)

Chordoma of skull base presenting as nasopharyngeal mass
por: Kataria, Sant Prakash, et al.
Publicado: (2013)

Genomic and transcriptomic characterization of skull base chordoma
por: Sa, Jason K., et al.
Publicado: (2016)

Clinical Implication of Systemic Immune-Inflammation Index and Prognostic Nutritional Index in Skull Base Chordoma Patients
por: Li, Mingxuan, et al.
Publicado: (2021)

Whole genome sequencing of skull-base chordoma reveals genomic alterations associated with recurrence and chordoma-specific survival
por: Bai, Jiwei, et al.
Publicado: (2021)

Unravelling the role of immune cells and FN1 in the recurrence and therapeutic process of skull base chordoma
por: Huo, Xulei, et al.
Publicado: (2023)

The role of Gamma Knife radiosurgery in the management of skull base chordoma
por: Wang, Kuanyu, et al.
Publicado: (2023)

State-of-the-Art Imaging in Human Chordoma of the Skull Base
por: Santegoeds, Rene G. C., et al.
Publicado: (2018)

Skull base chordomas review of current treatment paradigms
por: Yaniv, Dan, et al.
Publicado: (2020)

Metastatic skull base chordoma: A systematic review
por: Young, Kurtis, et al.
Publicado: (2022)

Mean platelet volume and platelet distribution width serve as prognostic biomarkers in skull base chordoma: a retrospective study
por: Li, Mingxuan, et al.
Publicado: (2020)

High systemic inflammation score is associated with adverse survival in skull base chordoma
por: Li, Mingxuan, et al.
Publicado: (2022)

Gamma Knife Management of Skull Base Chordomas: Is it a Choice?
por: Zakaria, Wael K., et al.
Publicado: (2018)

Ectopic Recurrence of Skull Base Chordoma after Proton Therapy
por: Santegoeds, René G. C., et al.
Publicado: (2022)

Chordoma at the skull base, spine, and sacrum: A pictorial essay
por: Lee, Sin Hang, et al.
Publicado: (2022)

Virus-like particle-based delivery of Cas9/guide RNA ribonucleoprotein efficiently edits the brachyury gene and inhibits chordoma growth in vivo
por: Hu, Yunping, et al.
Publicado: (2023)

PALB2 as a factor to predict the prognosis of patients with skull base chordoma
por: Xiong, Yujia, et al.
Publicado: (2022)

Clinicopathological significance of p16, cyclin D1, Rb and MIB-1 levels in skull base chordoma and chondrosarcoma
por: Liu, Jun-qi, et al.
Publicado: (2015)

Combined Application of Sodium Fluorescein and Neuronavigation Techniques in the Resection of Brain Gliomas
por: Xue, Zhan, et al.
Publicado: (2021)

Skull base chordoma presenting as nasopharyngeal mass with lymph node metastasis
por: Jain, Bhawna Bhutoria, et al.
Publicado: (2013)

Immunophenotypic features of dedifferentiated skull base chordoma: An insight into the intratumoural heterogeneity
por: Batista, Kelvin Manuel Piña, et al.
Publicado: (2017)

Skull base chordoma treated with proton therapy: A systematic review
por: Alahmari, Mohammed, et al.
Publicado: (2019)

Multimodal Intraoperative Image-Driven Surgery for Skull Base Chordomas and Chondrosarcomas
por: Essayed, Walid I., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_v15gmn32bvhfa9cf4cd08vplvu