Utilizing Murine Inducible Telomerase Alleles in the Studies of Tissue Degeneration/Regeneration and Cancer

Telomere dysfunction-induced loss of genome integrity and its associated DNA damage signaling and checkpoint responses are well-established drivers that cause tissue degeneration during ageing. Cancer, with incidence rates greatly increasing with age, is characterized by short telomere lengths and h...

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Detalles Bibliográficos
Autores principales: Shingu, Takashi, Jaskelioff, Mariela, Yuan, Liang, Ding, Zhihu, Protopopov, Alexei, Kost-Alimova, Maria, Hu, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2015
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526143/
https://www.ncbi.nlm.nih.gov/pubmed/25938254
http://dx.doi.org/10.3791/52599

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