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A varying T cell subtype explains apparent tobacco smoking induced single CpG hypomethylation in whole blood

BACKGROUND: Many recent epigenetic studies report that cigarette smoking reduces DNA methylation in whole blood at the single CpG site cg19859270 within the GPR15 gene. RESULTS: Within two independent cohorts, we confirmed the differentially expression of the GPR15 gene when smokers and non-smokers...

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Detalles Bibliográficos
Autores principales: Bauer, Mario, Linsel, Gunter, Fink, Beate, Offenberg, Kirsten, Hahn, Anne Maria, Sack, Ulrich, Knaack, Heike, Eszlinger, Markus, Herberth, Gunda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526203/
https://www.ncbi.nlm.nih.gov/pubmed/26246861
http://dx.doi.org/10.1186/s13148-015-0113-1