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Redeployment of Myc and E2f1-3 drives Rb deficient cell cycles
Robust mechanisms to control cell proliferation have evolved to maintain the integrity of organ architecture. Here, we investigated how two critical proliferative pathways, Myc and E2f, are integrated to control cell cycles in normal and Rb deficient cells using a murine intestinal model. We show th...
Autores principales: | Liu, Huayang, Tang, Xing, Srivastava, Arunima, Pécot, Thierry, Daniel, Piotr, Hemmelgarn, Benjamin, Reyes, Stephan, Fackler, Nicholas, Bajwa, Amneet, Kladney, Raleigh, Koivisto, Christopher, Chen, Zhong, Wang, Qianben, Huang, Kun, Machiraju, Raghu, Sáenz-Robles, Maria Teresa, Cantalupo, Paul, Pipas, James M., Leone, Gustavo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526313/ https://www.ncbi.nlm.nih.gov/pubmed/26192440 http://dx.doi.org/10.1038/ncb3210 |
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