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Redeployment of Myc and E2f1-3 drives Rb deficient cell cycles

Robust mechanisms to control cell proliferation have evolved to maintain the integrity of organ architecture. Here, we investigated how two critical proliferative pathways, Myc and E2f, are integrated to control cell cycles in normal and Rb deficient cells using a murine intestinal model. We show th...

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Detalles Bibliográficos
Autores principales: Liu, Huayang, Tang, Xing, Srivastava, Arunima, Pécot, Thierry, Daniel, Piotr, Hemmelgarn, Benjamin, Reyes, Stephan, Fackler, Nicholas, Bajwa, Amneet, Kladney, Raleigh, Koivisto, Christopher, Chen, Zhong, Wang, Qianben, Huang, Kun, Machiraju, Raghu, Sáenz-Robles, Maria Teresa, Cantalupo, Paul, Pipas, James M., Leone, Gustavo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526313/
https://www.ncbi.nlm.nih.gov/pubmed/26192440
http://dx.doi.org/10.1038/ncb3210

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