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Analysis of the anti-proliferative and the pro-apoptotic efficacy of Syk inhibition in multiple myeloma

BACKGROUND: Multiple myeloma (MM) is a clonal B cell malignancy characterized by proliferation of malignant plasma cells in the bone marrow. Despite high-dose melphalan therapy with autologous stem cell transplantation (ASCT) and the introduction of immunomodulatory drugs like bortezomib or lenalido...

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Detalles Bibliográficos
Autores principales:	Koerber, Ruth-Miriam, Held, Stefanie Andrea Erika, Heine, Annkristin, Kotthoff, Philipp, Daecke, Solveig Nora, Bringmann, Anita, Brossart, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526421/ https://www.ncbi.nlm.nih.gov/pubmed/26251761 http://dx.doi.org/10.1186/s40164-015-0016-z

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