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Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometric (LC/ESI-MS/MS) Study for the Identification and Characterization of In Vivo Metabolites of Cisplatin in Rat Kidney Cancer Tissues: Online Hydrogen/Deuterium (H/D) Exchange Study

In vivo rat kidney tissue metabolites of an anticancer drug, cisplatin (cis-diamminedichloroplatinum [II]) (CP) which is used for the treatment of testicular, ovarian, bladder, cervical, esophageal, small cell lung, head and neck cancers, have been identified and characterized by using liquid chroma...

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Detalles Bibliográficos
Autores principales:	Bandu, Raju, Ahn, Hyun Soo, Lee, Joon Won, Kim, Yong Woo, Choi, Seon Hee, Kim, Hak Jin, Kim, Kwang Pyo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526507/ https://www.ncbi.nlm.nih.gov/pubmed/26244343 http://dx.doi.org/10.1371/journal.pone.0134027

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