Let-7 Represses Carcinogenesis and a Stem Cell Phenotype in the Intestine via Regulation of Hmga2

Let-7 miRNAs comprise one of the largest and most highly expressed family of miRNAs among vertebrates, and is critical for promoting differentiation, regulating metabolism, inhibiting cellular proliferation, and repressing carcinogenesis in a variety of tissues. The large size of the Let-7 family of...

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Detalles Bibliográficos
Autores principales: Madison, Blair B., Jeganathan, Arjun N., Mizuno, Rei, Winslow, Monte M., Castells, Antoni, Cuatrecasas, Miriam, Rustgi, Anil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526516/
https://www.ncbi.nlm.nih.gov/pubmed/26244988
http://dx.doi.org/10.1371/journal.pgen.1005408

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