Evaluation of the therapeutic efficacy of a MEK inhibitor (TAK-733) using (18)F-fluorodeoxyglucose-positron emission tomography in the human lung xenograft model A549

OBJECTIVE: The aim of this study was to evaluate the potential of (18)F-fluorodeoxyglucose-positron emission tomography ((18)F-FDG-PET) for monitoring the therapeutic efficacy of TAK-733, an inhibitor of mitogen-activated protein kinase kinase, in nude rats bearing A549 (human lung carcinoma) xenogr...

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Detalles Bibliográficos
Autores principales: Ishino, Seigo, Miyake, Hiroshi, Vincent, Patrick, Mori, Ikuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526591/
https://www.ncbi.nlm.nih.gov/pubmed/26014721
http://dx.doi.org/10.1007/s12149-015-0984-4

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