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An Extended, Boolean Model of the Septation Initiation Network in S.Pombe Provides Insights into Its Regulation

Cytokinesis in fission yeast is controlled by the Septation Initiation Network (SIN), a protein kinase signaling network using the spindle pole body as scaffold. In order to describe the qualitative behavior of the system and predict unknown mutant behaviors we decided to adopt a Boolean modeling ap...

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Detalles Bibliográficos
Autores principales:	Chasapi, Anastasia, Wachowicz, Paulina, Niknejad, Anne, Collin, Philippe, Krapp, Andrea, Cano, Elena, Simanis, Viesturs, Xenarios, Ioannis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526654/ https://www.ncbi.nlm.nih.gov/pubmed/26244885 http://dx.doi.org/10.1371/journal.pone.0134214

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