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Likelihood of Null Effects of Large NHLBI Clinical Trials Has Increased over Time

BACKGROUND: We explore whether the number of null results in large National Heart Lung, and Blood Institute (NHLBI) funded trials has increased over time. METHODS: We identified all large NHLBI supported RCTs between 1970 and 2012 evaluating drugs or dietary supplements for the treatment or preventi...

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Detalles Bibliográficos
Autores principales:	Kaplan, Robert M., Irvin, Veronica L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526697/ https://www.ncbi.nlm.nih.gov/pubmed/26244868 http://dx.doi.org/10.1371/journal.pone.0132382

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