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A Simple Flow-Cytometric Method Measuring B Cell Surface Immunoglobulin Avidity Enables Characterization of Affinity Maturation to Influenza A Virus

Antibody (Ab) affinity maturation enables an individual to maintain immunity to an increasing number of pathogens within the limits of a total Ig production threshold. A better understanding of this process is critical for designing vaccines that generate optimal Ab responses to pathogens. Our study...

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Detalles Bibliográficos
Autores principales:	Frank, Gregory M., Angeletti, Davide, Ince, William L., Gibbs, James S., Khurana, Surender, Wheatley, Adam K., Max, Edward E., McDermott, Adrian B., Golding, Hana, Stevens, James, Bennink, Jack R., Yewdell, Jonathan W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Microbiology 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526714/ https://www.ncbi.nlm.nih.gov/pubmed/26242629 http://dx.doi.org/10.1128/mBio.01156-15

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