β-Catenin destruction complex-independent regulation of Hippo–YAP signaling by APC in intestinal tumorigenesis

Mutations in Adenomatous polyposis coli (APC) underlie familial adenomatous polyposis (FAP), an inherited cancer syndrome characterized by the widespread development of colorectal polyps. APC is best known as a scaffold protein in the β-catenin destruction complex, whose activity is antagonized by c...

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Detalles Bibliográficos
Autores principales: Cai, Jing, Maitra, Anirban, Anders, Robert A., Taketo, Makoto M., Pan, Duojia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526734/
https://www.ncbi.nlm.nih.gov/pubmed/26193883
http://dx.doi.org/10.1101/gad.264515.115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526734/
https://www.ncbi.nlm.nih.gov/pubmed/26193883
http://dx.doi.org/10.1101/gad.264515.115

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