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Albendazole induces oxidative stress and DNA damage in the parasitic protozoan Giardia duodenalis

The control of Giardia duodenalis infections is carried out mainly by drugs, among these albendazole (ABZ) is commonly used. Although the cytotoxic effect of ABZ usually involves binding to β-tubulin, it has been suggested that oxidative stress may also play a role in its parasiticidal mechanism. In...

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Detalles Bibliográficos
Autores principales: Martínez-Espinosa, Rodrigo, Argüello-García, Raúl, Saavedra, Emma, Ortega-Pierres, Guadalupe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526806/
https://www.ncbi.nlm.nih.gov/pubmed/26300866
http://dx.doi.org/10.3389/fmicb.2015.00800