Cargando…

Inhibition of protein kinase C by isojacareubin suppresses hepatocellular carcinoma metastasis and induces apoptosis in vitro and in vivo

Targeted inhibition of protein kinase C (PKC) inhibits hepatocellular carcinoma (HCC) proliferation and metastasis. We previously reported the cytotoxicity of a series of synthetic phenyl-substituted polyoxygenated xanthone derivatives against human HCC. In the current study, the most potent natural...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yuan, Xing, Chen, Hao, Li, Xia, Dai, Ming, Zeng, Huawu, Shan, Lei, Sun, Qingyan, Zhang, Weidong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526861/ https://www.ncbi.nlm.nih.gov/pubmed/26245668 http://dx.doi.org/10.1038/srep12889

Ejemplares similares

Isojacareubin from the Chinese Herb Hypericum japonicum: Potent Antibacterial and Synergistic Effects on Clinical Methicillin-Resistant Staphylococcus aureus (MRSA)
por: Zuo, Guo-Ying, et al.
Publicado: (2012)

Betulinic acid induces apoptosis and suppresses metastasis in hepatocellular carcinoma cell lines in vitro and in vivo
por: Wang, Wei, et al.
Publicado: (2018)

AMP-Activated Protein Kinase Suppresses the In Vitro and In Vivo Proliferation of Hepatocellular Carcinoma
por: Cheng, Jidong, et al.
Publicado: (2014)

Ascorbic Acid Inhibits Liver Cancer Growth and Metastasis in vitro and in vivo, Independent of Stemness Gene Regulation
por: Wan, Jingjing, et al.
Publicado: (2021)

Resistomycin Induced Apoptosis and Cycle Arrest in Human Hepatocellular Carcinoma Cells by Activating p38 MAPK Pathway In Vitro and In Vivo
por: Han, Zhuo, et al.
Publicado: (2021)

Theaflavins suppress tumor growth and metastasis via the blockage of the STAT3 pathway in hepatocellular carcinoma
por: Shao, Jianping, et al.
Publicado: (2016)

Potential diagnostic and prognostic marker dimethylglycine dehydrogenase (DMGDH) suppresses hepatocellular carcinoma metastasis in vitro and in vivo
por: Liu, Gang, et al.
Publicado: (2016)

Baicalein Selectively Induces Apoptosis in Activated Lymphocytes and Ameliorates Concanavalin A-Induced Hepatitis in Mice
por: Zhang, Yan, et al.
Publicado: (2013)

NRP-1 silencing suppresses hepatocellular carcinoma cell growth in vitro and in vivo
por: XU, JING, et al.
Publicado: (2013)

Midazolam Suppresses Hepatocellular Carcinoma Cell Metastasis and Enhances Apoptosis by Elevating miR-217
por: Shen, Qian, et al.
Publicado: (2022)

SWELL1 promotes cell growth and metastasis of hepatocellular carcinoma in vitro and in vivo
por: Lu, Panpan, et al.
Publicado: (2019)

Xihuang pills induce apoptosis in hepatocellular carcinoma by suppressing phosphoinositide 3-kinase/protein kinase-B/mechanistic target of rapamycin pathway
por: Teng, Yong-Jie, et al.
Publicado: (2022)

Metformin prevents methylglyoxal-induced apoptosis by suppressing oxidative stress in vitro and in vivo
por: Wang, Gang, et al.
Publicado: (2022)

Salinomycin Inhibits Proliferation and Induces Apoptosis of Human Hepatocellular Carcinoma Cells In Vitro and In Vivo
por: Wang, Fan, et al.
Publicado: (2012)

Tetrandrine suppresses cervical cancer growth by inducing apoptosis in vitro and in vivo
por: Zhang, Haiyan, et al.
Publicado: (2018)

Suppression of Lung Metastasis by Aspirin but Not Indomethacin in an in vivo Model of Chemically Induced Hepatocellular Carcinoma
por: Futakuchi, Mitsuru, et al.
Publicado: (2002)

Dermcidin Enhances the Migration, Invasion, and Metastasis of Hepatocellular Carcinoma Cells In Vitro and In Vivo
por: Qiu, Fanghua, et al.
Publicado: (2022)

Atractylon induces apoptosis and suppresses metastasis in hepatic cancer cells and inhibits growth in vivo
por: Cheng, Yang, et al.
Publicado: (2019)

Methionine deprivation suppresses triple-negative breast cancer metastasis in vitro and in vivo
por: Jeon, Hyein, et al.
Publicado: (2016)

In Vivo and In Vitro Suppression of Hepatocellular Carcinoma by EF24, a Curcumin Analog
por: Liu, Haitao, et al.
Publicado: (2012)

Bisimidazolium Salt Glycosyltransferase Inhibitors Suppress Hepatocellular Carcinoma Progression In Vitro and In Vivo
por: Luan, Xue, et al.
Publicado: (2022)

Retracted: Midazolam Suppresses Hepatocellular Carcinoma Cell Metastasis and Enhances Apoptosis by Elevating miR-217
por: Methods in Medicine, Computational and Mathematical
Publicado: (2023)

Apoptosis signal-regulating kinase 1 inhibition in in vivo and in vitro models of pulmonary hypertension
por: Wilson, Kathryn S., et al.
Publicado: (2020)

MT-12 inhibits the growth and metastasis of bladder cancer cells via suppressing tumor angiogenesis in vivo and in vitro
por: Xia, Chengxing, et al.
Publicado: (2019)

Pharmacological inhibition of USP7 suppresses growth and metastasis of melanoma cells in vitro and in vivo
por: Xiang, Minmin, et al.
Publicado: (2021)

Ethanol extract of Ligustrum lucidum Ait. leaves suppressed hepatocellular carcinoma in vitro and in vivo
por: Tian, Guoyan, et al.
Publicado: (2019)

KIFC1 promotes the proliferation of hepatocellular carcinoma in vitro and in vivo
por: Wang, Xing, et al.
Publicado: (2019)

Anti-angiogenesis and anti-metastasis effects of Polyphyllin VII on Hepatocellular carcinoma cells in vitro and in vivo
por: Zhang, Chao, et al.
Publicado: (2021)

Transcutaneous Carbon Dioxide Induces Mitochondrial Apoptosis and Suppresses Metastasis of Oral Squamous Cell Carcinoma In Vivo
por: Takeda, Daisuke, et al.
Publicado: (2014)

Breast Cancer Metastasis Suppressor 1 Regulates Hepatocellular Carcinoma Cell Apoptosis via Suppressing Osteopontin Expression
por: Wu, Yanhua, et al.
Publicado: (2012)

Recombinant adenovirus IL-24-Bax promotes apoptosis of hepatocellular carcinoma cells in vitro and in vivo
por: Li, J, et al.
Publicado: (2010)

Knockdown of CD44 inhibits the invasion and metastasis of hepatocellular carcinoma both in vitro and in vivo by reversing epithelial-mesenchymal transition
por: Gao, Yuan, et al.
Publicado: (2015)

NF-κB suppresses apoptosis and promotes bladder cancer cell proliferation by upregulating survivin expression in vitro and in vivo
por: Cui, Xiaolu, et al.
Publicado: (2017)

In vitro and in vivo study of epigallocatechin-3-gallate-induced apoptosis in aerobic glycolytic hepatocellular carcinoma cells involving inhibition of phosphofructokinase activity
por: Li, Sainan, et al.
Publicado: (2016)

In Vitro and In Vivo Anticancer Activity of Gimatecan against Hepatocellular Carcinoma
por: Zhao, Youna, et al.
Publicado: (2016)

Inhibition of hyaluronan retention by 4-methylumbelliferone suppresses osteosarcoma cells in vitro and lung metastasis in vivo
por: Arai, E, et al.
Publicado: (2011)

[Retracted] KIFC1 promotes the proliferation of hepatocellular carcinoma in vitro and in vivo
por: Wang, Xing, et al.
Publicado: (2023)

Exploring the Mechanism of Flaccidoxide-13-Acetate in Suppressing Cell Metastasis of Hepatocellular Carcinoma
por: Wu, Yu-Jen, et al.
Publicado: (2020)

Peretinoin, an acyclic retinoid, inhibits hepatocarcinogenesis by suppressing sphingosine kinase 1 expression in vitro and in vivo
por: Funaki, Masaya, et al.
Publicado: (2017)

Bioinformatic Analysis and In Vitro and In Vivo Experiments Reveal That Fibrillarin Participates in the Promotion of Lung Metastasis in Hepatocellular Carcinoma
por: Luo, Weixin, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_dbn94u2s5jj3defbcs9s76pt8p