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Inhibition of protein kinase C by isojacareubin suppresses hepatocellular carcinoma metastasis and induces apoptosis in vitro and in vivo
Targeted inhibition of protein kinase C (PKC) inhibits hepatocellular carcinoma (HCC) proliferation and metastasis. We previously reported the cytotoxicity of a series of synthetic phenyl-substituted polyoxygenated xanthone derivatives against human HCC. In the current study, the most potent natural...
Autores principales: | Yuan, Xing, Chen, Hao, Li, Xia, Dai, Ming, Zeng, Huawu, Shan, Lei, Sun, Qingyan, Zhang, Weidong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526861/ https://www.ncbi.nlm.nih.gov/pubmed/26245668 http://dx.doi.org/10.1038/srep12889 |
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