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RNA Binds to Tau Fibrils and Sustains Template-Assisted Growth

[Image: see text] Tau fibrils are the main proteinacious components of neurofibrillary lesions in Alzheimer disease. Although RNA molecules are sequestered into these lesions, their relationship to Tau fibrils is only poorly understood. Such understanding, however, is important, as short fibrils can...

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Detalles Bibliográficos
Autores principales: Dinkel, Paul D., Holden, Michael R., Matin, Nadira, Margittai, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526887/
https://www.ncbi.nlm.nih.gov/pubmed/26177386
http://dx.doi.org/10.1021/acs.biochem.5b00453