Oxcarbazepine induced toxic epidermal necrolysis - a rare case report

Carbamazepine, is well known to cause Stevens–Johnson syndrome and toxic epidermal necrolysis(TEN). Oxcarbazepine, a 10-keto analog of carbamazepine, is an anticholinergic, anticonvulsant and mood stabilizing drug, used primarily in the treatment of epilepsy. Its efficacy is similar to carbamazepine...

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Autores principales: Guleria, Vivek S., Sharda, Chetan, Rana, Tanuja, Sood, A. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Drug Watch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527075/
https://www.ncbi.nlm.nih.gov/pubmed/26288485
http://dx.doi.org/10.4103/0253-7613.161279
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author Guleria, Vivek S.
Sharda, Chetan
Rana, Tanuja
Sood, A. K.
author_facet Guleria, Vivek S.
Sharda, Chetan
Rana, Tanuja
Sood, A. K.
author_sort Guleria, Vivek S.
collection PubMed
description Carbamazepine, is well known to cause Stevens–Johnson syndrome and toxic epidermal necrolysis(TEN). Oxcarbazepine, a 10-keto analog of carbamazepine, is an anticholinergic, anticonvulsant and mood stabilizing drug, used primarily in the treatment of epilepsy. Its efficacy is similar to carbamazepine but allergic reactions and enzyme induction is low. We describe a case of oxcarbazepine induced TEN, who presented with erythematous ulcerative maculopapular rash.
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spelling pubmed-45270752015-08-18 Oxcarbazepine induced toxic epidermal necrolysis - a rare case report Guleria, Vivek S. Sharda, Chetan Rana, Tanuja Sood, A. K. Indian J Pharmacol Drug Watch Carbamazepine, is well known to cause Stevens–Johnson syndrome and toxic epidermal necrolysis(TEN). Oxcarbazepine, a 10-keto analog of carbamazepine, is an anticholinergic, anticonvulsant and mood stabilizing drug, used primarily in the treatment of epilepsy. Its efficacy is similar to carbamazepine but allergic reactions and enzyme induction is low. We describe a case of oxcarbazepine induced TEN, who presented with erythematous ulcerative maculopapular rash. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4527075/ /pubmed/26288485 http://dx.doi.org/10.4103/0253-7613.161279 Text en Copyright: © Indian Journal of Pharmacology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Drug Watch
Guleria, Vivek S.
Sharda, Chetan
Rana, Tanuja
Sood, A. K.
Oxcarbazepine induced toxic epidermal necrolysis - a rare case report
title Oxcarbazepine induced toxic epidermal necrolysis - a rare case report
title_full Oxcarbazepine induced toxic epidermal necrolysis - a rare case report
title_fullStr Oxcarbazepine induced toxic epidermal necrolysis - a rare case report
title_full_unstemmed Oxcarbazepine induced toxic epidermal necrolysis - a rare case report
title_short Oxcarbazepine induced toxic epidermal necrolysis - a rare case report
title_sort oxcarbazepine induced toxic epidermal necrolysis - a rare case report
topic Drug Watch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527075/
https://www.ncbi.nlm.nih.gov/pubmed/26288485
http://dx.doi.org/10.4103/0253-7613.161279
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AT soodak oxcarbazepineinducedtoxicepidermalnecrolysisararecasereport

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