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Selective enhancement of insulin sensitivity in the mature adipocyte is sufficient for systemic metabolic improvements
Dysfunctional adipose tissue represents a hallmark of type 2 diabetes and systemic insulin resistance, characterized by fibrotic deposition of collagens and increased immune cell infiltration within the depots. Here we generate an inducible model of loss of function of the protein phosphatase and te...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527086/ https://www.ncbi.nlm.nih.gov/pubmed/26243466 http://dx.doi.org/10.1038/ncomms8906 |