MicroRNA-101 is repressed by EZH2 and its restoration inhibits tumorigenic features in embryonal rhabdomyosarcoma

BACKGROUND: Rhabdomyosarcoma (RMS) is a pediatric soft tissue sarcoma arising from myogenic precursors that have lost their capability to differentiate into skeletal muscle. The polycomb-group protein EZH2 is a Lys27 histone H3 methyltransferase that regulates the balance between cell proliferation...

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Detalles Bibliográficos
Autores principales: Vella, Serena, Pomella, Silvia, Leoncini, Pier Paolo, Colletti, Marta, Conti, Beatrice, Marquez, Victor E., Strillacci, Antonio, Roma, Josep, Gallego, Soledad, Milano, Giuseppe M., Capogrossi, Maurizio C., Bertaina, Alice, Ciarapica, Roberta, Rota, Rossella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527101/
https://www.ncbi.nlm.nih.gov/pubmed/26251675
http://dx.doi.org/10.1186/s13148-015-0107-z

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