HMGB1: a novel protein that induced platelets active and aggregation via Toll-like receptor-4, NF-κB and cGMP dependent mechanisms

BACKGROUND: Thrombotic diseases are a group of prevalent and life-threatening diseases. Selective inhibition of pathological thrombosis holds the key to treat variety of thrombotic diseases. The pathological thrombosis can be induced by either tissue necrosis and deregulated inflammation. HMGB1, as...

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Detalles Bibliográficos
Autores principales: Yang, Xinyu, Wang, Haichao, Zhang, Menmen, Liu, Jin, Lv, Ben, Chen, Fangping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527107/
https://www.ncbi.nlm.nih.gov/pubmed/26245198
http://dx.doi.org/10.1186/s13000-015-0348-3

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