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In vitro response pattern of monocytes after tmTNF reverse signaling predicts response to anti-TNF therapy in rheumatoid arthritis
BACKGROUND: Treatment with TNF inhibitors is very efficient in the majority of the patients with rheumatoid arthritis (RA), but it does not achieve a sufficient treatment response in 40–50% of the cases. Goal of the study was to assess functional ex vivo-tests of RA monocytes as prognostic parameter...
Autores principales: | Meusch, Undine, Krasselt, Marco, Rossol, Manuela, Baerwald, Christoph, Klingner, Maria, Wagner, Ulf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527214/ https://www.ncbi.nlm.nih.gov/pubmed/26251236 http://dx.doi.org/10.1186/s12967-015-0620-z |
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