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MicroRNA-16 suppresses metastasis in an orthotopic, but not autochthonous, mouse model of soft tissue sarcoma

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MicroRNAs (miRNAs) can regulate tumor cell invasion and metastasis in a tumor-specific manner. We recently demonstrated that global downregulation of miRNAs after deleting dicer can promote development of distant metastases in a mouse model of primary soft tissue sarcoma (STS). In this study, we ide...

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Detalles Bibliográficos
Autores principales:	Sachdeva, Mohit, Whitley, Melody J., Mito, Jeffrey K., Ma, Yan, Lev, Dina C., Cardona, Diana M., Kirsch, David G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527278/ https://www.ncbi.nlm.nih.gov/pubmed/26044957 http://dx.doi.org/10.1242/dmm.017897

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