MicroRNA-16 suppresses metastasis in an orthotopic, but not autochthonous, mouse model of soft tissue sarcoma

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MicroRNAs (miRNAs) can regulate tumor cell invasion and metastasis in a tumor-specific manner. We recently demonstrated that global downregulation of miRNAs after deleting dicer can promote development of distant metastases in a mouse model of primary soft tissue sarcoma (STS). In this study, we ide...

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Detalles Bibliográficos
Autores principales: Sachdeva, Mohit, Whitley, Melody J., Mito, Jeffrey K., Ma, Yan, Lev, Dina C., Cardona, Diana M., Kirsch, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527278/
https://www.ncbi.nlm.nih.gov/pubmed/26044957
http://dx.doi.org/10.1242/dmm.017897
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