Cargando…
Effects of FSGS-associated mutations on the stability and function of myosin-1 in fission yeast
Point mutations in the human MYO1E gene, encoding class I myosin Myo1e, are associated with focal segmental glomerulosclerosis (FSGS), a primary kidney disorder that leads to end-stage kidney disease. In this study, we used a simple model organism, fission yeast Schizosaccharomyces pombe, to test th...
Autores principales: | Bi, Jing, Carroll, Robert T., James, Michael L., Ouderkirk, Jessica L., Krendel, Mira, Sirotkin, Vladimir |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527290/ https://www.ncbi.nlm.nih.gov/pubmed/26092123 http://dx.doi.org/10.1242/dmm.020214 |
Ejemplares similares
-
UCS Protein Rng3p Is Essential for Myosin-II Motor Activity during Cytokinesis in Fission Yeast
por: Stark, Benjamin C., et al.
Publicado: (2013) -
Myosin 1e promotes breast cancer malignancy by enhancing tumor cell proliferation and stimulating tumor cell de-differentiation
por: Ouderkirk-Pecone, Jessica L., et al.
Publicado: (2016) -
Interactions of WASp, myosin-I, and verprolin with Arp2/3 complex during actin patch assembly in fission yeast
por: Sirotkin, Vladimir, et al.
Publicado: (2005) -
Hic-5 Remodeling of the Stromal Matrix Promotes Breast Tumor Progression
por: Goreczny, Gregory J., et al.
Publicado: (2016) -
Myosin Vs organize actin cables in fission yeast
por: Lo Presti, Libera, et al.
Publicado: (2012)