Phospholamban overexpression in mice causes a centronuclear myopathy-like phenotype

Centronuclear myopathy (CNM) is a congenital myopathy that is histopathologically characterized by centrally located nuclei, central aggregation of oxidative activity, and type I fiber predominance and hypotrophy. Here, we obtained commercially available mice overexpressing phospholamban (Pln(OE)),...

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Detalles Bibliográficos
Autores principales: Fajardo, Val A., Bombardier, Eric, McMillan, Elliott, Tran, Khanh, Wadsworth, Brennan J., Gamu, Daniel, Hopf, Andrew, Vigna, Chris, Smith, Ian C., Bellissimo, Catherine, Michel, Robin N., Tarnopolsky, Mark A., Quadrilatero, Joe, Tupling, A. Russell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Resource Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527296/
https://www.ncbi.nlm.nih.gov/pubmed/26035394
http://dx.doi.org/10.1242/dmm.020859

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