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Impact of Expression Levels of Platinum-uptake Transporters Copper Transporter 1 and Organic Cation Transporter 2 on Resistance to Anthracycline/Taxane-based Chemotherapy in Triple-negative Breast Cancer

Adding platinum drugs to anthracycline/taxane (ANC-Tax)-based neoadjuvant chemotherapy (NAC) improves pathological complete response (pCR) rates in triple-negative breast cancer (TNBC). Copper transporter 1 (CTR1) and organic cation transporter 2 (OCT2) critically affect the uptake and cytotoxicity...

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Detalles Bibliográficos
Autores principales:	Takeda, Risa, Naka, Ayano, Ogane, Naoki, Kameda, Yoichi, Kawachi, Kae, Shimizu, Satoru, Kamoshida, Shingo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Libertas Academica 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527352/ https://www.ncbi.nlm.nih.gov/pubmed/26309405 http://dx.doi.org/10.4137/BCBCR.S27534

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