The role of neighboring infected cattle in bovine leukemia virus transmission risk

A cohort study was conducted to evaluate the risk of bovine leukemia virus (BLV) transmission to uninfected cattle by adjacent infected cattle in 6 dairy farms. Animals were initially tested in 2010–2011 using a commercial ELISA kit. Uninfected cattle were repeatedly tested every 4 to 6 months until...

Descripción completa

Detalles Bibliográficos
Autores principales: KOBAYASHI, Sota, TSUTSUI, Toshiyuki, YAMAMOTO, Takehisa, HAYAMA, Yoko, MUROGA, Norihiko, KONISHI, Misako, KAMEYAMA, Ken-ichiro, MURAKAMI, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2015
Materias:
Virology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527511/
https://www.ncbi.nlm.nih.gov/pubmed/25754652
http://dx.doi.org/10.1292/jvms.15-0007
_version_ 1782384576937590784
author KOBAYASHI, Sota
TSUTSUI, Toshiyuki
YAMAMOTO, Takehisa
HAYAMA, Yoko
MUROGA, Norihiko
KONISHI, Misako
KAMEYAMA, Ken-ichiro
MURAKAMI, Kenji
author_facet KOBAYASHI, Sota
TSUTSUI, Toshiyuki
YAMAMOTO, Takehisa
HAYAMA, Yoko
MUROGA, Norihiko
KONISHI, Misako
KAMEYAMA, Ken-ichiro
MURAKAMI, Kenji
author_sort KOBAYASHI, Sota
collection PubMed
description A cohort study was conducted to evaluate the risk of bovine leukemia virus (BLV) transmission to uninfected cattle by adjacent infected cattle in 6 dairy farms. Animals were initially tested in 2010–2011 using a commercial ELISA kit. Uninfected cattle were repeatedly tested every 4 to 6 months until fall of 2012. The Cox proportional hazard model with frailty showed that uninfected cattle neighboring to infected cattle (n=53) had a significant higher risk of seroconversion than those without any infected neighbors (n=81) (hazard ratio: 12.4, P=0.001), implying that neighboring infected cattle were a significant risk factor for BLV transmission. This finding provides scientific support for animal health authorities and farmers to segregate infected cattle on farms to prevent spread of BLV.
format Online
Article
Text
id pubmed-4527511
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher The Japanese Society of Veterinary Science
record_format MEDLINE/PubMed
spelling pubmed-45275112015-08-07 The role of neighboring infected cattle in bovine leukemia virus transmission risk KOBAYASHI, Sota TSUTSUI, Toshiyuki YAMAMOTO, Takehisa HAYAMA, Yoko MUROGA, Norihiko KONISHI, Misako KAMEYAMA, Ken-ichiro MURAKAMI, Kenji J Vet Med Sci Virology A cohort study was conducted to evaluate the risk of bovine leukemia virus (BLV) transmission to uninfected cattle by adjacent infected cattle in 6 dairy farms. Animals were initially tested in 2010–2011 using a commercial ELISA kit. Uninfected cattle were repeatedly tested every 4 to 6 months until fall of 2012. The Cox proportional hazard model with frailty showed that uninfected cattle neighboring to infected cattle (n=53) had a significant higher risk of seroconversion than those without any infected neighbors (n=81) (hazard ratio: 12.4, P=0.001), implying that neighboring infected cattle were a significant risk factor for BLV transmission. This finding provides scientific support for animal health authorities and farmers to segregate infected cattle on farms to prevent spread of BLV. The Japanese Society of Veterinary Science 2015-03-05 2015-07 /pmc/articles/PMC4527511/ /pubmed/25754652 http://dx.doi.org/10.1292/jvms.15-0007 Text en ©2015 The Japanese Society of Veterinary Science http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License.
spellingShingle Virology
KOBAYASHI, Sota
TSUTSUI, Toshiyuki
YAMAMOTO, Takehisa
HAYAMA, Yoko
MUROGA, Norihiko
KONISHI, Misako
KAMEYAMA, Ken-ichiro
MURAKAMI, Kenji
The role of neighboring infected cattle in bovine leukemia virus transmission risk
title The role of neighboring infected cattle in bovine leukemia virus transmission risk
title_full The role of neighboring infected cattle in bovine leukemia virus transmission risk
title_fullStr The role of neighboring infected cattle in bovine leukemia virus transmission risk
title_full_unstemmed The role of neighboring infected cattle in bovine leukemia virus transmission risk
title_short The role of neighboring infected cattle in bovine leukemia virus transmission risk
title_sort role of neighboring infected cattle in bovine leukemia virus transmission risk
topic Virology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527511/
https://www.ncbi.nlm.nih.gov/pubmed/25754652
http://dx.doi.org/10.1292/jvms.15-0007
work_keys_str_mv AT kobayashisota theroleofneighboringinfectedcattleinbovineleukemiavirustransmissionrisk
AT tsutsuitoshiyuki theroleofneighboringinfectedcattleinbovineleukemiavirustransmissionrisk
AT yamamototakehisa theroleofneighboringinfectedcattleinbovineleukemiavirustransmissionrisk
AT hayamayoko theroleofneighboringinfectedcattleinbovineleukemiavirustransmissionrisk
AT muroganorihiko theroleofneighboringinfectedcattleinbovineleukemiavirustransmissionrisk
AT konishimisako theroleofneighboringinfectedcattleinbovineleukemiavirustransmissionrisk
AT kameyamakenichiro theroleofneighboringinfectedcattleinbovineleukemiavirustransmissionrisk
AT murakamikenji theroleofneighboringinfectedcattleinbovineleukemiavirustransmissionrisk
AT kobayashisota roleofneighboringinfectedcattleinbovineleukemiavirustransmissionrisk
AT tsutsuitoshiyuki roleofneighboringinfectedcattleinbovineleukemiavirustransmissionrisk
AT yamamototakehisa roleofneighboringinfectedcattleinbovineleukemiavirustransmissionrisk
AT hayamayoko roleofneighboringinfectedcattleinbovineleukemiavirustransmissionrisk
AT muroganorihiko roleofneighboringinfectedcattleinbovineleukemiavirustransmissionrisk
AT konishimisako roleofneighboringinfectedcattleinbovineleukemiavirustransmissionrisk
AT kameyamakenichiro roleofneighboringinfectedcattleinbovineleukemiavirustransmissionrisk
AT murakamikenji roleofneighboringinfectedcattleinbovineleukemiavirustransmissionrisk

Ejemplares similares