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Plasma fluctuation in estradiol-17β and bone resorption markers around parturition in dairy cows
Blood samples were obtained sequentially from 10 dairy cows around the time of parturition to assess plasma fluctuations in estradiol-17β (E(2)) levels in association with those of several bone resorption markers. Plasma E(2) concentration increased sharply a few days prepartum and decreased quickly...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Japanese Society of Veterinary Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527514/ https://www.ncbi.nlm.nih.gov/pubmed/25755022 http://dx.doi.org/10.1292/jvms.15-0018 |
| Sumario: | Blood samples were obtained sequentially from 10 dairy cows around the time of parturition to assess plasma fluctuations in estradiol-17β (E(2)) levels in association with those of several bone resorption markers. Plasma E(2) concentration increased sharply a few days prepartum and decreased quickly after parturition. In terms of bone resorption markers, the plasma level of tartrate-resistant acid phosphatase isoform 5b (TRAP5b) rose significantly, commencing 1 week prepartum, and was maintained at this level to a few days postpartum. The plasma concentration of carboxyterminal collagen cross-links of type-I collagen (CTx) increased significantly after parturition. These observations suggest that osteoclast-mediated bone resorption was activated after parturition when plasma E(2) concentrations decreased. |
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