Plasma fluctuation in estradiol-17β and bone resorption markers around parturition in dairy cows

Blood samples were obtained sequentially from 10 dairy cows around the time of parturition to assess plasma fluctuations in estradiol-17β (E(2)) levels in association with those of several bone resorption markers. Plasma E(2) concentration increased sharply a few days prepartum and decreased quickly...

Descripción completa

Detalles Bibliográficos
Autores principales: DEVKOTA, Bhuminad, TAKAHASHI, Masahiro, SATO, Saori, SASAKI, Kouya, UEKI, Atsushi, OSAWA, Takeshi, YAMAGISHI, Norio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2015
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527514/
https://www.ncbi.nlm.nih.gov/pubmed/25755022
http://dx.doi.org/10.1292/jvms.15-0018
_version_ 1782384577600290816
author DEVKOTA, Bhuminad
TAKAHASHI, Masahiro
SATO, Saori
SASAKI, Kouya
UEKI, Atsushi
OSAWA, Takeshi
TAKAHASHI, Masahiro
YAMAGISHI, Norio
author_facet DEVKOTA, Bhuminad
TAKAHASHI, Masahiro
SATO, Saori
SASAKI, Kouya
UEKI, Atsushi
OSAWA, Takeshi
TAKAHASHI, Masahiro
YAMAGISHI, Norio
author_sort DEVKOTA, Bhuminad
collection PubMed
description Blood samples were obtained sequentially from 10 dairy cows around the time of parturition to assess plasma fluctuations in estradiol-17β (E(2)) levels in association with those of several bone resorption markers. Plasma E(2) concentration increased sharply a few days prepartum and decreased quickly after parturition. In terms of bone resorption markers, the plasma level of tartrate-resistant acid phosphatase isoform 5b (TRAP5b) rose significantly, commencing 1 week prepartum, and was maintained at this level to a few days postpartum. The plasma concentration of carboxyterminal collagen cross-links of type-I collagen (CTx) increased significantly after parturition. These observations suggest that osteoclast-mediated bone resorption was activated after parturition when plasma E(2) concentrations decreased.
format Online
Article
Text
id pubmed-4527514
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher The Japanese Society of Veterinary Science
record_format MEDLINE/PubMed
spelling pubmed-45275142015-08-07 Plasma fluctuation in estradiol-17β and bone resorption markers around parturition in dairy cows DEVKOTA, Bhuminad TAKAHASHI, Masahiro SATO, Saori SASAKI, Kouya UEKI, Atsushi OSAWA, Takeshi TAKAHASHI, Masahiro YAMAGISHI, Norio J Vet Med Sci Internal Medicine Blood samples were obtained sequentially from 10 dairy cows around the time of parturition to assess plasma fluctuations in estradiol-17β (E(2)) levels in association with those of several bone resorption markers. Plasma E(2) concentration increased sharply a few days prepartum and decreased quickly after parturition. In terms of bone resorption markers, the plasma level of tartrate-resistant acid phosphatase isoform 5b (TRAP5b) rose significantly, commencing 1 week prepartum, and was maintained at this level to a few days postpartum. The plasma concentration of carboxyterminal collagen cross-links of type-I collagen (CTx) increased significantly after parturition. These observations suggest that osteoclast-mediated bone resorption was activated after parturition when plasma E(2) concentrations decreased. The Japanese Society of Veterinary Science 2015-03-09 2015-07 /pmc/articles/PMC4527514/ /pubmed/25755022 http://dx.doi.org/10.1292/jvms.15-0018 Text en ©2015 The Japanese Society of Veterinary Science http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License.
spellingShingle Internal Medicine
DEVKOTA, Bhuminad
TAKAHASHI, Masahiro
SATO, Saori
SASAKI, Kouya
UEKI, Atsushi
OSAWA, Takeshi
TAKAHASHI, Masahiro
YAMAGISHI, Norio
Plasma fluctuation in estradiol-17β and bone resorption markers around parturition in dairy cows
title Plasma fluctuation in estradiol-17β and bone resorption markers around parturition in dairy cows
title_full Plasma fluctuation in estradiol-17β and bone resorption markers around parturition in dairy cows
title_fullStr Plasma fluctuation in estradiol-17β and bone resorption markers around parturition in dairy cows
title_full_unstemmed Plasma fluctuation in estradiol-17β and bone resorption markers around parturition in dairy cows
title_short Plasma fluctuation in estradiol-17β and bone resorption markers around parturition in dairy cows
title_sort plasma fluctuation in estradiol-17β and bone resorption markers around parturition in dairy cows
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527514/
https://www.ncbi.nlm.nih.gov/pubmed/25755022
http://dx.doi.org/10.1292/jvms.15-0018
work_keys_str_mv AT devkotabhuminad plasmafluctuationinestradiol17bandboneresorptionmarkersaroundparturitionindairycows
AT takahashimasahiro plasmafluctuationinestradiol17bandboneresorptionmarkersaroundparturitionindairycows
AT satosaori plasmafluctuationinestradiol17bandboneresorptionmarkersaroundparturitionindairycows
AT sasakikouya plasmafluctuationinestradiol17bandboneresorptionmarkersaroundparturitionindairycows
AT uekiatsushi plasmafluctuationinestradiol17bandboneresorptionmarkersaroundparturitionindairycows
AT osawatakeshi plasmafluctuationinestradiol17bandboneresorptionmarkersaroundparturitionindairycows
AT takahashimasahiro plasmafluctuationinestradiol17bandboneresorptionmarkersaroundparturitionindairycows
AT yamagishinorio plasmafluctuationinestradiol17bandboneresorptionmarkersaroundparturitionindairycows

Ejemplares similares