Treatment of HIV-Infected Subjects with Buttock Lipoatrophy Using Stabilized Hyaluronic Acid Gel

This prospective study explored effectiveness and safety of Macrolane VRF30 for treatment of buttock lipoatrophy in HIV-infected subjects. Ten subjects who were unable to sit for more than 30 minutes because of pain were injected with a mean of 276 mL and followed for 18 months. The pain score was r...

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Autores principales: Claude, Olivier, Bosc, Romain, Pigneur, Fréderic, Lantieri, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2015
Materias:
Ideas and Innovations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527640/
https://www.ncbi.nlm.nih.gov/pubmed/26301155
http://dx.doi.org/10.1097/GOX.0000000000000423
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author Claude, Olivier
Bosc, Romain
Pigneur, Fréderic
Lantieri, Laurent
author_facet Claude, Olivier
Bosc, Romain
Pigneur, Fréderic
Lantieri, Laurent
author_sort Claude, Olivier
collection PubMed
description This prospective study explored effectiveness and safety of Macrolane VRF30 for treatment of buttock lipoatrophy in HIV-infected subjects. Ten subjects who were unable to sit for more than 30 minutes because of pain were injected with a mean of 276 mL and followed for 18 months. The pain score was reduced, and the time that subjects could sit was increased at least up to 9 months post treatment. There was no local displacement of gel. Five mild adverse events occurred; all related to the injection procedure. This pilot study indicates that Macrolane treatment of buttock lipoatrophy is a promising, well-tolerated method that reduces pain at sitting and improves buttock appearance.
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spelling pubmed-45276402015-08-21 Treatment of HIV-Infected Subjects with Buttock Lipoatrophy Using Stabilized Hyaluronic Acid Gel Claude, Olivier Bosc, Romain Pigneur, Fréderic Lantieri, Laurent Plast Reconstr Surg Glob Open Ideas and Innovations This prospective study explored effectiveness and safety of Macrolane VRF30 for treatment of buttock lipoatrophy in HIV-infected subjects. Ten subjects who were unable to sit for more than 30 minutes because of pain were injected with a mean of 276 mL and followed for 18 months. The pain score was reduced, and the time that subjects could sit was increased at least up to 9 months post treatment. There was no local displacement of gel. Five mild adverse events occurred; all related to the injection procedure. This pilot study indicates that Macrolane treatment of buttock lipoatrophy is a promising, well-tolerated method that reduces pain at sitting and improves buttock appearance. Wolters Kluwer Health 2015-08-10 /pmc/articles/PMC4527640/ /pubmed/26301155 http://dx.doi.org/10.1097/GOX.0000000000000423 Text en Copyright © 2015 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The American Society of Plastic Surgeons. All rights reserved. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License, where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially.
spellingShingle Ideas and Innovations
Claude, Olivier
Bosc, Romain
Pigneur, Fréderic
Lantieri, Laurent
Treatment of HIV-Infected Subjects with Buttock Lipoatrophy Using Stabilized Hyaluronic Acid Gel
title Treatment of HIV-Infected Subjects with Buttock Lipoatrophy Using Stabilized Hyaluronic Acid Gel
title_full Treatment of HIV-Infected Subjects with Buttock Lipoatrophy Using Stabilized Hyaluronic Acid Gel
title_fullStr Treatment of HIV-Infected Subjects with Buttock Lipoatrophy Using Stabilized Hyaluronic Acid Gel
title_full_unstemmed Treatment of HIV-Infected Subjects with Buttock Lipoatrophy Using Stabilized Hyaluronic Acid Gel
title_short Treatment of HIV-Infected Subjects with Buttock Lipoatrophy Using Stabilized Hyaluronic Acid Gel
title_sort treatment of hiv-infected subjects with buttock lipoatrophy using stabilized hyaluronic acid gel
topic Ideas and Innovations
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527640/
https://www.ncbi.nlm.nih.gov/pubmed/26301155
http://dx.doi.org/10.1097/GOX.0000000000000423
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