SPARC Controls Melanoma Cell Plasticity through Rac1

Cell transition to a more aggressive mesenchymal-like phenotype is a hallmark of cancer progression that involves different steps and requires tightly regulated cell plasticity. SPARC (Secreted Protein Acidic and Rich in Cysteine) is a matricellular protein that promotes this transition in various m...

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Detalles Bibliográficos
Autores principales: Salvatierra, Edgardo, Alvarez, Mariano J., Leishman, Claudia C., Rivas Baquero, Elvia, Lutzky, Viviana P., Chuluyan, H. Eduardo, Podhajcer, Osvaldo L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527691/
https://www.ncbi.nlm.nih.gov/pubmed/26248315
http://dx.doi.org/10.1371/journal.pone.0134714

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