Lithium Modulates Autophagy in Esophageal and Colorectal Cancer Cells and Enhances the Efficacy of Therapeutic Agents In Vitro and In Vivo

Many epithelial cancers, particularly gastrointestinal tract cancers, remain poor prognosis diseases, due to resistance to cytotoxic therapy and local or metastatic recurrence. We have previously shown that apoptosis incompetent esophageal cancer cells induce autophagy in response to chemotherapeuti...

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Detalles Bibliográficos
Autores principales: O’Donovan, Tracey R., Rajendran, Simon, O’Reilly, Seamus, O’Sullivan, Gerald C., McKenna, Sharon L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527721/
https://www.ncbi.nlm.nih.gov/pubmed/26248051
http://dx.doi.org/10.1371/journal.pone.0134676

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