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Transgenic Rabbits Expressing Ovine PrP Are Susceptible to Scrapie
Transmissible spongiform encephalopathies (TSEs) are a group of neurodegenerative diseases affecting a wide range of mammalian species. They are caused by prions, a proteinaceous pathogen essentially composed of PrP(Sc), an abnormal isoform of the host encoded cellular prion protein PrPC. Constraine...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527776/ https://www.ncbi.nlm.nih.gov/pubmed/26248157 http://dx.doi.org/10.1371/journal.ppat.1005077 |