Ibrutinib and rituximab induced rapid response in refractory Richter syndrome

We report a 53-year-old man diagnosed with Richter syndrome. He was heavily pretreated and was refractory to prior therapy. He received rituximab and ibrutinib, and achieved a significant response after 1 month of therapy. Our case illustrates the importance of investigation of rituximab and ibrutin...

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Detalles Bibliográficos
Autores principales: Lamar, Zanetta, Kennedy, LeAnne, Kennedy, Brooke, Lynch, Mary, Goad, Amanda, Hurd, David, McIver, Zachariah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527807/
https://www.ncbi.nlm.nih.gov/pubmed/26273453
http://dx.doi.org/10.1002/ccr3.269
Descripción
Sumario:We report a 53-year-old man diagnosed with Richter syndrome. He was heavily pretreated and was refractory to prior therapy. He received rituximab and ibrutinib, and achieved a significant response after 1 month of therapy. Our case illustrates the importance of investigation of rituximab and ibrutinib in Richter’s syndrome.

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