Ibrutinib and rituximab induced rapid response in refractory Richter syndrome

We report a 53-year-old man diagnosed with Richter syndrome. He was heavily pretreated and was refractory to prior therapy. He received rituximab and ibrutinib, and achieved a significant response after 1 month of therapy. Our case illustrates the importance of investigation of rituximab and ibrutin...

Descripción completa

Detalles Bibliográficos
Autores principales: Lamar, Zanetta, Kennedy, LeAnne, Kennedy, Brooke, Lynch, Mary, Goad, Amanda, Hurd, David, McIver, Zachariah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527807/
https://www.ncbi.nlm.nih.gov/pubmed/26273453
http://dx.doi.org/10.1002/ccr3.269
_version_ 1782384622246559744
author Lamar, Zanetta
Kennedy, LeAnne
Kennedy, Brooke
Lynch, Mary
Goad, Amanda
Hurd, David
McIver, Zachariah
author_facet Lamar, Zanetta
Kennedy, LeAnne
Kennedy, Brooke
Lynch, Mary
Goad, Amanda
Hurd, David
McIver, Zachariah
author_sort Lamar, Zanetta
collection PubMed
description We report a 53-year-old man diagnosed with Richter syndrome. He was heavily pretreated and was refractory to prior therapy. He received rituximab and ibrutinib, and achieved a significant response after 1 month of therapy. Our case illustrates the importance of investigation of rituximab and ibrutinib in Richter’s syndrome.
format Online
Article
Text
id pubmed-4527807
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher John Wiley & Sons, Ltd
record_format MEDLINE/PubMed
spelling pubmed-45278072015-08-13 Ibrutinib and rituximab induced rapid response in refractory Richter syndrome Lamar, Zanetta Kennedy, LeAnne Kennedy, Brooke Lynch, Mary Goad, Amanda Hurd, David McIver, Zachariah Clin Case Rep Case Reports We report a 53-year-old man diagnosed with Richter syndrome. He was heavily pretreated and was refractory to prior therapy. He received rituximab and ibrutinib, and achieved a significant response after 1 month of therapy. Our case illustrates the importance of investigation of rituximab and ibrutinib in Richter’s syndrome. John Wiley & Sons, Ltd 2015-07 2015-06-05 /pmc/articles/PMC4527807/ /pubmed/26273453 http://dx.doi.org/10.1002/ccr3.269 Text en © 2015 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. http://creativecommons.org/licenses/by-nc/4.0/ This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Reports
Lamar, Zanetta
Kennedy, LeAnne
Kennedy, Brooke
Lynch, Mary
Goad, Amanda
Hurd, David
McIver, Zachariah
Ibrutinib and rituximab induced rapid response in refractory Richter syndrome
title Ibrutinib and rituximab induced rapid response in refractory Richter syndrome
title_full Ibrutinib and rituximab induced rapid response in refractory Richter syndrome
title_fullStr Ibrutinib and rituximab induced rapid response in refractory Richter syndrome
title_full_unstemmed Ibrutinib and rituximab induced rapid response in refractory Richter syndrome
title_short Ibrutinib and rituximab induced rapid response in refractory Richter syndrome
title_sort ibrutinib and rituximab induced rapid response in refractory richter syndrome
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527807/
https://www.ncbi.nlm.nih.gov/pubmed/26273453
http://dx.doi.org/10.1002/ccr3.269
work_keys_str_mv AT lamarzanetta ibrutinibandrituximabinducedrapidresponseinrefractoryrichtersyndrome
AT kennedyleanne ibrutinibandrituximabinducedrapidresponseinrefractoryrichtersyndrome
AT kennedybrooke ibrutinibandrituximabinducedrapidresponseinrefractoryrichtersyndrome
AT lynchmary ibrutinibandrituximabinducedrapidresponseinrefractoryrichtersyndrome
AT goadamanda ibrutinibandrituximabinducedrapidresponseinrefractoryrichtersyndrome
AT hurddavid ibrutinibandrituximabinducedrapidresponseinrefractoryrichtersyndrome
AT mciverzachariah ibrutinibandrituximabinducedrapidresponseinrefractoryrichtersyndrome

Ejemplares similares