Immunogenicity of pneumococcal vaccination in a patient with sickle hemoglobinopathy: a case report

Despite decrease in morbidity and mortality from invasive pneumococcal disease (IPD), individuals with asplenia remain at risk for IPD compared to the general population. This report describes a young adult with hemoglobin SD and documented splenic autoinfarction with pneumococcal sepsis, meningitis...

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Detalles Bibliográficos
Autores principales: Clay, E Leila Jerome, Burrell, Tierra, Belhorn, Thomas, Redding-Lallinger, Rupa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527808/
https://www.ncbi.nlm.nih.gov/pubmed/26273454
http://dx.doi.org/10.1002/ccr3.276
Descripción
Sumario:Despite decrease in morbidity and mortality from invasive pneumococcal disease (IPD), individuals with asplenia remain at risk for IPD compared to the general population. This report describes a young adult with hemoglobin SD and documented splenic autoinfarction with pneumococcal sepsis, meningitis, and pneumonia within seven months of immunization with PPSV-23.

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